Dragonfly 3D World News

先进微电子封装的翘曲会在 X 射线 CT 数据中引入几何畸变，导致各层混叠、难以判读。本研究在 Dragonfly 3D World 软件中实现了一套数字矫形工作流：基于径向基函数（RBF）的曲面拟合生成形变场，再对体数据做体积变换，得到平面化的 CT 数据以便逐层对齐分析。以倒装芯片针栅阵列（FCPGA）封装为例，该工作流显著改善了各封装层的分离与判读效果。Warpage in advanced microelectronic packages introduces geometric distortion in X-ray CT datasets, mixing layers and limiting interpretability. This work implements a digital de-warping workflow in Dragonfly 3D World software: radial-basis-function (RBF) surface fitting generates a deformation field that is applied to the volume, producing planarized CT data for layer-aligned analysis. Demonstrated on flip-chip pin grid array (FCPGA) packages, the workflow markedly improves isolation and interpretation of individual package layers.

黄病毒（登革、寨卡等）每年造成约四亿人感染，其基因组复制依赖宿主内质网中的病毒复制细胞器（vRO）。本研究发现 Atlastin-2 介导的内质网膜系留是 vRO 形成与黄病毒复制的关键机制。作者结合电子断层成像，在 Dragonfly 3D World 软件（Comet Technologies Canada）中对 vRO 进行了人工分割与三维重构，以解析膜重塑结构。Flaviviruses (dengue, Zika and relatives) cause roughly 400 million human infections per year, replicating inside viral replication organelles (vROs) derived from host endoplasmic reticulum. The study shows Atlastin-2-mediated ER membrane tethering is critical for vRO biogenesis and flavivirus replication. Using electron tomography, the authors manually segmented and reconstructed vROs in 3D with Dragonfly 3D World software (Comet Technologies Canada) to characterize the membrane-remodeling structures.